Top 10 Drugs That Cause Kidney Damage

Top 10 Drugs That Cause Kidney Damage
Top 10 Drugs That Cause Kidney Damage


We are all aware that the kidneys are one of the essential organs in the human body. It is because they help us flush out and eliminate all toxins and excess salt from the organism. This is the reason why you should take good care of them and cleanse them from time to time. You shall as well know that our kidneys absorb some of the sodium and the harmful toxins from time to time – and sand and stones as well. However, did you know that certain drugs and medications can cause kidney damage as well? The answer is actually yes, and you shall avoid these drugs in the future.

  • Antibiotics– methicillin, vancomycin, ciprofloxacin, sulfonamides.
  • Rheumatoid arthritis drugs– infliximab (brand name Remicade); chloroquine and hydroxychloroquine, which are used for treating malaria and systemic lupus erythematosus as well as rheumatoid arthritis.
  • Lithium
  • Anticonvulsants– phenytoin (brand name Dilantin) and trimethadione (brand name Tridione), used to treat seizures and other conditions.
  • Antiviral drugs– acyclovir (brand name Zovirax) used to treat herpes infection, and indinavir and tenofovir, both used to treat HIV.
  • High blood pressure drugs– captopril (brand name Capoten).
  • Chemotherapy drugs– cyclosporine, tacrolimus, quinine, interferons, pamidronate, cisplatin, carboplatin, mitomycin C, bevacizumab; and anti-thyroid drugs, including propylthiouracil, that are used to treat overactive thyroid.
  • Analgesics– acetaminophen and also non-steroidal anti-inflammatory drugs (NSAID): naproxen, aspirin, ibuprofen, and others available only by prescription.
  • COX-2 inhibitors– celecoxib (brand name Celebrex). There exist two drugs in this class that have been withdrawn from the market because of cardiovascular toxicity: rofecoxib (brand name Vioxx) and valdecoxib (brand name Bextra). These kinds of drugs are a particular class of NSAIDs that were developed to be safer for the stomach, but have the same risk as other NSAIDs for kidney damage.
  • Heartburn drugs of the proton pump inhibitor class, while also including omeprazole (brand name Prilosec), lansoprazole (brand name Prevacid), pantoprazole (brand name Protonix), rabeprazole (brand names Rabecid, Aciphex), esomeprazole (brand names Nexium, Esotrex). See Ref. 4.

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